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HSFY1 encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Name: | heat shock transcription factor, Y-linked 1 |
Family/Subfamily: | Transcription Factor |
Synonyms: | HSFY1, HSFY, HSF2-like, HSF2L |
Target Sequences: | NM_033108 NP_149099.2 |
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