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HSD17B8 / RING2

hydroxysteroid (17-beta) dehydrogenase 8

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Gene Name: hydroxysteroid (17-beta) dehydrogenase 8
Synonyms: HSD17B8, 17-beta-HSD 8, Estrogen 17-oxidoreductase, H2-KE6, HKE6, Ke-6, FABG, KE6, Protein Ke6, SDR30C1, D6S2245E, DJ1033B10.9, FABGL, RING2
Target Sequences: D82061 BAA11529.1 Q92506

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
HSD17B8 / RING2 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
HSD17B8 / RING2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
26.8 kDa
100 µg/$494
HSD17B8 / RING2 Protein - 12.5% SDS-PAGE of human HSD17B8 stained with Coomassie Blue
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Wheat Germ Extract
GST
53.4 kDa
10 µg/$479; 25 µg/$670
HSD17B8 / RING2 Protein - Purified recombinant protein HSD17B8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.8 kDa
20 µg/$1,107
HSD17B8 / RING2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HSD17B8 / RING2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.8 kDa
20 µg/$150
HSD17B8 / RING2 Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).