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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HSD17B8 / RING2

hydroxysteroid (17-beta) dehydrogenase 8

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Gene Name: hydroxysteroid (17-beta) dehydrogenase 8
Synonyms: HSD17B8, 17-beta-HSD 8, Estrogen 17-oxidoreductase, H2-KE6, HKE6, Ke-6, FABG, KE6, Protein Ke6, SDR30C1, D6S2245E, DJ1033B10.9, FABGL, RING2
Target Sequences: D82061 BAA11529.1 Q92506

Filtered By: None
Target
HSD17B8 / RING2 (22)
Reactivity
Human (22)
Mouse (3)
Rat (3)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Application
IHC (6)
IHC-P (5)
WB (22)
ELISA (4)
IP (1)
Peptide-ELISA (1)
Host
rabbit (18)
mouse (4)
Isotype
IgG (14)
IgG1 (2)
IgG1,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (19)
Clone
2E12 (1)
4F1 (1)
6H2 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa51-100 (4)
aa33-67 (1)
aa57-261 (1)
Publications
No (22)
Showing 1-22 of 22 results

HSD17B8 / RING2 Antibody IHC-plus™ LS-B15313
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
60µl  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE); at a dilution of 1:100
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE); at a dilution of 1:100
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100

HSD17B8 / RING2 Antibody (aa57-261, clone 2E12) LS-C336980
Mouse Monoclonal [clone 2E12] (IgG1) to Human HSD17B8 / RING2
Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-HSD17B8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Western blot of extracts (35ug) from 9 different cell lines by using anti-HSD17B8 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-HSD17B8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Western blot of extracts (35ug) from 9 different cell lines by using anti-HSD17B8 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

HSD17B8 / RING2 Antibody IHC-plus™ LS-B15539
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

HSD17B8 / RING2 Antibody IHC-plus™ LS-B15321
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
60µl  $425.00
Human Testis, Leydig Cells: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 1:100
Immunohistochemistry of Human liver cancer using HSD17B8 Polyclonal Antibody at dilution of 1:55.
Human Testis, Leydig Cells: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 1:100
Immunohistochemistry of Human liver cancer using HSD17B8 Polyclonal Antibody at dilution of 1:55.

HSD17B8 / RING2 Antibody (clone 6H2) LS-C175393
Mouse Monoclonal [clone 6H2] (IgG1) to Human HSD17B8 / RING2
Dog, Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-HSD17B8 mouse monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-HSD17B8 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC of paraffin-embedded Carcinoma of Human liver tissue using anti-HSD17B8 mouse monoclonal antibody.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-HSD17B8 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

HSD17B8 / RING2 Antibody LS-C666234
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

HSD17B8 / RING2 Antibody (clone 4F1) LS-C198512
Mouse Monoclonal [clone 4F1] (IgG1,k) to Human HSD17B8 / RING2
Human
ELISA WB
Unconjugated
100µg  $355.00
HSD17B8 monoclonal antibody (M01), clone 4F1. Western Blot analysis of HSD17B8 expression in human pancreas.
Detection limit for recombinant GST tagged HSD17B8 is 0.1 ng/ml as a capture antibody.
HSD17B8 monoclonal antibody (M01), clone 4F1. Western Blot analysis of HSD17B8 expression in human pancreas.
Detection limit for recombinant GST tagged HSD17B8 is 0.1 ng/ml as a capture antibody.

HSD17B8 / RING2 Antibody LS-C311236
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
IP WB
Unconjugated
100µl  $605.00

HSD17B8 / RING2 Antibody (aa33-67) LS-C392865
Rabbit Polyclonal to Human HSD17B8 / RING2
Human
Peptide-ELISA WB
Unconjugated
50µl  $205.00
All lanes: Anti-HSD17B8 Antibody (N-term) at 1:2000 dilution. Lane 1: human liver lysate. Lane 2: human pancreas lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 27 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
All lanes: Anti-HSD17B8 Antibody (N-term) at 1:2000 dilution. Lane 1: human liver lysate. Lane 2: human pancreas lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 27 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

HSD17B8 / RING2 Antibody LS-C311237
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
Unconjugated
100µg  $605.00

HSD17B8 / RING2 Antibody (HRP) LS-C542588
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
HRP Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (Biotin) LS-C522456
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
Biotin Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (FITC) LS-C532500
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
FITC Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (AP) LS-C504534
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
AP Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (PE) LS-C650700
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
PE Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (APC) LS-C514242
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
APC Conjugated
100µl  $755.00

HSD17B8 / RING2 Antibody (aa51-100) LS-C146002
Rabbit Polyclonal to Human HSD17B8 / RING2
Human
WB
Unconjugated
50µg  $365.00
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HSD17B8 / RING2 Antibody (aa51-100, HRP) LS-C469470
Rabbit Polyclonal to Human HSD17B8 / RING2
Human, Chimpanzee, Gibbon
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HSD17B8 / RING2 Antibody (aa51-100, Biotin) LS-C469468
Rabbit Polyclonal to Human HSD17B8 / RING2
Human, Chimpanzee, Gibbon
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HSD17B8 / RING2 Antibody (aa51-100, FITC) LS-C469469
Rabbit Polyclonal to Human HSD17B8 / RING2
Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl 1mg/ml  $385.00
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HSD17B8 antibody Western blot of 8226 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HSD17B8 / RING2 Antibody LS-C748014
Rabbit Polyclonal (IgG) to Human HSD17B8 / RING2
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using HSD17B8 Antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of various cell lines, using HSD17B8 Antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.

HSD17B8 / RING2 Antibody LS-C308326
Mouse Polyclonal (IgG) to Human HSD17B8 / RING2
Human
WB
Unconjugated
50µg  $560.00
Showing 1-22 of 22 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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