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HSD17B4

Hydroxysteroid (17-beta) Dehydrogenase 4

HSD17B4 is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Hydroxysteroid (17-beta) Dehydrogenase 4
Synonyms: HSD17B4, 17-beta-HSD IV, 17-beta-HSD 4, Beta-keto-reductase, D-bifunctional protein, EDH17B4, MPF-2, PRLTS1, SDR8C1, Beta-hydroxyacyl dehydrogenase, MFE-2, Multifunctional protein 2
Target Sequences: NM_000414 NP_000405.1 P51659

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
HSD17B4 (4)
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His (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Yeast (1)
HSD17B4 Protein - Purified recombinant protein HSD17B4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
79.5 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
79.5 kDa
20 µg/$150
HSD17B4 Protein
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Yeast
His
81.69 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
HSD17B4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
79.5 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).