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Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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HSD17B4
Hydroxysteroid (17-beta) Dehydrogenase 4
HSD17B4 is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Gene Name: | Hydroxysteroid (17-beta) Dehydrogenase 4 |
| Synonyms: | HSD17B4, 17-beta-HSD IV, 17-beta-HSD 4, Beta-keto-reductase, D-bifunctional protein, EDH17B4, MPF-2, PRLTS1, SDR8C1, Beta-hydroxyacyl dehydrogenase, MFE-2, Multifunctional protein 2 |
| Target Sequences: | NM_000414 NP_000405.1 P51659 |
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