HSD17B12

hydroxysteroid (17-beta) dehydrogenase 12

Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women. Also has 3-ketoacyl-CoA reductase activity, reducing both long chain 3-ketoacyl-CoAs and long chain fatty acyl-CoAs, suggesting a role in long fatty acid elongation.

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Proteins (5)

Type

Recombinant (5)

Target

HSD17B12 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST (2)

Species

Human (3)

Mouse (1)

Rat (1)

Source

E. coli (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human HSD17B12 Protein (Recombinant GST) (Full Length) - LS-G33647

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

36.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HSD17B12 Protein (Recombinant His) (aa1-312) - LS-G25564

Source:

E. coli

Tag:

His

Molecular Weight:

38.0 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human HSD17B12 Protein (Recombinant GST, N-terminus) (aa203-271) - LS-G62411

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse HSD17B12 Protein (Recombinant His-GST) (aa1-312) - LS-G15604

Source:

E. coli

Tag:

His-GST

Molecular Weight:

61.8 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat HSD17B12 Protein (Recombinant His-GST) (aa11-291) - LS-G15603

Source:

E. coli

Tag:

His-GST

Molecular Weight:

58.3 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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