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HSD17B11

hydroxysteroid (17-beta) dehydrogenase 11

Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Gene Name: hydroxysteroid (17-beta) dehydrogenase 11
Synonyms: HSD17B11, 17-beta-HSD 11, 17-BETA-HSDXI, 17betaHSD11, 17-beta-HSD XI, 17-BETA-HSD11, 17betaHSDXI, 17BHSD11, CTCL tumor antigen HD-CL-03, DHRS8, RetSDR2, SDR16C2, PAN1B
Target Sequences: NM_016245 NP_057329.3 Q8NBQ5

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
HSD17B11 (6)
No (6)
GST (1)
His (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
HSD17B11 Protein - Purified recombinant protein HSD17B11 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
32.8 kDa
20 µg/$1,107
HSD17B11 Protein
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E. coli
His-SUMO
46.8 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HSD17B11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.8 kDa
20 µg/$150
HSD17B11 Protein - 12.5% SDS-PAGE of human HSD17B11 stained with Coomassie Blue
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Wheat Germ Extract
GST
59.4 kDa
2 µg/$439
HSD17B11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.8 kDa
100 µg/$494
HSD17B11 Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).