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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
| Gene Name: | hydroxysteroid (17-beta) dehydrogenase 11 |
| Synonyms: | HSD17B11, 17-beta-HSD 11, 17-BETA-HSDXI, 17betaHSD11, 17-beta-HSD XI, 17-BETA-HSD11, 17betaHSDXI, 17BHSD11, CTCL tumor antigen HD-CL-03, DHRS8, RetSDR2, SDR16C2, PAN1B |
| Target Sequences: | NM_016245 NP_057329.3 Q8NBQ5 |
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