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HSD17B10 / HADH2

hydroxysteroid (17-beta) dehydrogenase 10

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Gene Name: hydroxysteroid (17-beta) dehydrogenase 10
Synonyms: HSD17B10, 17-beta-HSD 10, 17b-HSD10, CAMR, DUPXp11.22, ABAD, ERAB, HADH2, MHBD, MRPP2, MRX17, SCHAD, SDR5C1, MRX31, MRXS10, Type II HADH, HCD2, XH98G2
Target Sequences: NM_004493 NP_004484.1 Q99714

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ELISA Kits (9)
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HSD17B10 / HADH2 (9)
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96-Well Microplate (2)
96-Well Strip Plate (7)
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Adherent Cell Cultures (1)
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Plasma (4)
Serum (4)
Tissue Homogenates (3)
HSD17B10 / HADH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
HSD17B10 / HADH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
HSD17B10 / HADH2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
HSD17B10 / HADH2 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
HSD17B10 / HADH2 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
HSD17B10 / HADH2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
25 - 1600 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
HSD17B10 / HADH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
HSD17B10 / HADH2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$854
HSD17B10 / HADH2 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).