HSD11B1 / HSD11B

hydroxysteroid (11-beta) dehydrogenase 1

HSD11B1 / HSD11B is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

HSD11B1 / HSD11B (9)

Publications

No (9)

Tag

GST (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Rat (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human HSD11B1 / HSD11B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65307

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

20 µg/$1,107

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Human HSD11B1 / HSD11B Protein (Recombinant His-SUMO) (aa25-292) - LS-G20834

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

45.5 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HSD11B1 / HSD11B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65306

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

20 µg/$1,107

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Rat HSD11B1 / HSD11B Protein (Recombinant His-T7) (aa1-288) - LS-G24733

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.6 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human HSD11B1 / HSD11B Protein (Recombinant GST) (Full Length) - LS-G28925

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.86 kDa

Price:

10 µg/$479; 25 µg/$670

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HSD11B1 / HSD11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G104385

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

100 µg/$494

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HSD11B1 / HSD11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100581

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

100 µg/$494

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Human HSD11B1 / HSD11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75312

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

20 µg/$150

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Human HSD11B1 / HSD11B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75313

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

20 µg/$150

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