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The protein encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases. A pseudogene located on chromosome 1 has been found for this gene.
Gene Name: | heparan sulfate 6-O-sulfotransferase 1 |
Synonyms: | HS6ST1, HH15, HS6ST-1, HS6ST |
Target Sequences: | NM_004807 NP_004798.3 O60243 |
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