HR6B / UBE2B

ubiquitin-conjugating enzyme E2B

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.

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Products

Antibodies (15)

Type

Primary (15)

Target

HR6B / UBE2B (15)

Reactivity

Human (15)

Mouse (4)

Rat (3)

Application

IHC (11)

IHC-P (2)

WB (15)

ELISA (8)

Host

rabbit (12)

mouse (3)

Isotype

IgG (9)

IgG2a,k (1)

IgG2b (2)

Clonality

monoclonal mc (3)

polyclonal pc (12)

Clone

4C3 (1)

OTI1E11 (2)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

Carrier-free (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (10)

Epitope

aa117-146 (7)

Publications

No (15)

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HR6B / UBE2B Antibody (aa117-146) LS-C98024

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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HR6B / UBE2B Antibody (aa117-146) LS-C328989

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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HR6B / UBE2B Antibody (aa117-146, Biotin) LS-C283916

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HR6B / UBE2B Antibody (aa117-146, FITC) LS-C283918

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HR6B / UBE2B Antibody (aa117-146, APC) LS-C283917

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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HR6B / UBE2B Antibody (aa117-146, PE) LS-C283920

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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HR6B / UBE2B Antibody (aa117-146, Azide-free, HRP) LS-C283919

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal (aa117-146) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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HR6B / UBE2B Antibody LS-C661372

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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HR6B / UBE2B Antibody LS-C334634

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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HR6B / UBE2B Antibody LS-C482567

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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HR6B / UBE2B Antibody LS-C771562

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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HR6B / UBE2B Antibody (clone 4C3) LS-C198393

Antibody:

HR6B / UBE2B Mouse anti-Human Monoclonal (4C3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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HR6B / UBE2B Antibody (clone OTI1E11) LS-C338792

Antibody:

HR6B / UBE2B Mouse anti-Human Monoclonal (OTI1E11) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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HR6B / UBE2B Antibody (clone OTI1E11, Carrier-free) LS-C798070

Antibody:

HR6B / UBE2B Mouse anti-Human Monoclonal (Carrier-free) (OTI1E11) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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HR6B / UBE2B Antibody LS-C109312

Antibody:

HR6B / UBE2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$450

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