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HOXB6

homeobox B6

HOXB6 is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.

Gene Name: homeobox B6
Synonyms: HOXB6, Hox-2.2, HOX2B, Homeo box B6, Homeobox protein Hox-2.2, HU-2, Homeobox protein Hox-2B, Homeobox protein Hox-B6, Hox-b6, Homeo box 2B, Homeobox B6, Homeobox protein Hu-2, HOX2
Target Sequences: NM_018952 NP_061825.2 P17509

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).