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HOOK1

hook microtubule-tethering protein 1

Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).

Gene Name:	hook microtubule-tethering protein 1
Synonyms:	HOOK1, H-hook1, HHK1, Hook homolog 1 (Drosophila), Protein Hook homolog 1
Target Sequences:	NM_015888 NP_056972.1 Q9UJC3

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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