HOMER1 / Homer 1

homer homolog 1 (Drosophila)

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

HOMER1 / Homer 1 (6)

Publications

No (6)

Tag

GST (1)

His (2)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human HOMER1 / Homer 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89247

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.1 kDa

Price:

20 µg/$150

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Human HOMER1 / Homer 1 Protein (Recombinant His) (Full Length) - LS-G22193

Source:

E. coli

Tag:

His

Molecular Weight:

44.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HOMER1 / Homer 1 Protein (Recombinant GST) (Full Length) - LS-G31642

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64.68 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HOMER1 / Homer 1 Protein (Recombinant His, N-Terminal) - LS-G144453

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

40.1 kDa

Price:

50 µg/$419

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Human HOMER1 / Homer 1 Protein (Recombinant His) - LS-G533

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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HOMER1 / Homer 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116759

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.1 kDa

Price:

100 µg/$494

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