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HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.

Gene Name: heterogeneous nuclear ribonucleoprotein A2/B1
Synonyms: HNRNPA2B1, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, HnRNP A2 / hnRNP B1, SNRPB1, HnRNP A2/B1, HNRNPA2, RNPA2
Target Sequences: NM_002137 NP_002128.1 P22626

Publications (1)

1
Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli. Heedoo Lee, Chunhua Li, Yang Zhang, Duo Zhang, Leo E Otterbein, Yang Jin. The Journal of experimental medicine. 2019 September;216:2202-2220. [Full Text Article] [PubMed:31235510] [PMC:PMC6719430]

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Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
HNRNPA2B1 (11)
No (10)
Yes (1)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
6His-B2M, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (4)
Cow (1)
Human (8)
Mouse (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Yeast (1)
Purified (5)
HNRNPA2B1 Protein
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Yeast
6His, N-terminus
30.4 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
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E. coli
6His-B2M, N-terminus
42.4 kDa
100 µg/$420; 1 mg/$1,355; 20 µg/$323
HNRNPA2B1 Protein - Purified recombinant protein HNRNPA2B1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.2 kDa
20 µg/$1,107
HNRNPA2B1 Protein - Purified recombinant protein HNRNPA2B1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
35.8 kDa
20 µg/$1,107
HNRNPA2B1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
HNRNPA2B1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-SUMO, N-terminus + Myc, C-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
HNRNPA2B1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
55.4kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HNRNPA2B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.8 kDa
20 µg/$150
HNRNPA2B1 Protein - Recombinant Heterogeneous Nuclear Ribonucleoprotein A2/B1 By SDS-PAGE
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E. coli
His
10.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
HNRNPA2B1 Protein - 12.5% SDS-PAGE of human HNRPA2B1 stained with Coomassie Blue
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Wheat Germ Extract
GST
53.13 kDa
10 µg/$479; 25 µg/$670
HNRNPA2B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.8 kDa
100 µg/$494
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).