HNRNP-E2 / PCBP2

poly(rC) binding protein 2

HNRNP-E2 / PCBP2 appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (19)

Type

Over-Expression Lysate (12)

Recombinant (7)

Target

HNRNP-E2 / PCBP2 (19)

Publications

No (19)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (17)

Species

Human (13)

Source

293T Cells (6)

HEK 293 Cells (11)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human HNRNP-E2 / PCBP2 Protein (Recombinant GST, N-terminus) (aa174-283) - LS-G59520

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83812

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83815

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83814

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.3 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83816

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83817

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83818

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38 kDa

Price:

20 µg/$150

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Human HNRNP-E2 / PCBP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69086

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38 kDa

Price:

20 µg/$1,107

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Human HNRNP-E2 / PCBP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69087

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

20 µg/$1,107

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Human HNRNP-E2 / PCBP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69088

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

20 µg/$1,107

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Human HNRNP-E2 / PCBP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69089

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.3 kDa

Price:

20 µg/$1,107

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Human HNRNP-E2 / PCBP2 Protein (Recombinant GST) (Full Length) - LS-G29634

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.56 kDa

Price:

10 µg/$479; 25 µg/$670

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HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102018

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38 kDa

Price:

100 µg/$494

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HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124863

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

100 µg/$494

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HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124864

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.3 kDa

Price:

100 µg/$494

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HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116234

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

100 µg/$494

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HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126964

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

100 µg/$494

Select

HNRNP-E2 / PCBP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119271

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

100 µg/$494

Select

Human HNRNP-E2 / PCBP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69085

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.5 kDa

Price:

20 µg/$1,107

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