HnRNP-E1 / PCBP1

poly(rC) binding protein 1

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

HnRNP-E1 / PCBP1 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human HnRNP-E1 / PCBP1 Protein (Recombinant GST, N-terminus) (aa181-280) - LS-G59517

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HnRNP-E1 / PCBP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68115

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.3 kDa

Price:

20 µg/$1,107

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Human HnRNP-E1 / PCBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81476

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.3 kDa

Price:

20 µg/$150

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Human HnRNP-E1 / PCBP1 Protein (Recombinant His) (Asp2-Cys356) - LS-G97748

Source:

E. coli

Tag:

His

Molecular Weight:

38.3 kDa

Price:

100 µg/$721

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Human HnRNP-E1 / PCBP1 Protein (Recombinant GST) (Full Length) - LS-G29633

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.9 kDa

Price:

10 µg/$479; 25 µg/$670

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HnRNP-E1 / PCBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100750

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.3 kDa

Price:

100 µg/$494

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Human HnRNP-E1 / PCBP1 Protein (Recombinant His) - LS-G2531

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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