HNE / Neutrophil Elastase

elastase, neutrophil expressed

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

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Products

ELISA Kits (31)

Type

Competitive EIA (4)

Custom (1)

Sandwich (23)

Sandwich CLIA (3)

Target

HNE / Neutrophil Elastase (31)

Reactivity

Human (9)

Mouse (9)

Rat (7)

Dog (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (2)

96-Well Strip Plate (25)

Publications

No (29)

Yes (2)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (2)

Cell Supernatant (2)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (27)

Serum (28)

Tissue Homogenates (5)

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Monkey HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F43441

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F22767

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F20775

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Pig HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F36096

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F11365

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat HNE / Neutrophil Elastase (CLIA) ELISA Kit - LS-F31099

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F4355

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.188 - 12 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Rat HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F4131

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$818

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Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F39774

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$795

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Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F5219

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$695

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Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F11364

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Guinea pig HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F43442

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rabbit HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F43443

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F51829

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$1,041

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Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F74812

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

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Porcine HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F75049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$669

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Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F57412

Type:

Sandwich

Reactivity:

Human

Range:

312 - 20000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Rat HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F56389

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat HNE / Neutrophil Elastase (Custom ELISA) ELISA Kit - LS-F13940

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human HNE / Neutrophil Elastase (CLIA) ELISA Kit - LS-F30169

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F27088

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse HNE / Neutrophil Elastase (Competitive EIA) ELISA Kit - LS-F28496

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Mouse HNE / Neutrophil Elastase (CLIA) ELISA Kit - LS-F30642

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Mouse HNE / Neutrophil Elastase (Sandwich ELISA) ELISA Kit - LS-F31720

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Mouse HNE / Neutrophil Elastase (Competitive EIA) ELISA Kit - LS-F28573

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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