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HMOX1 / HO-1
heme oxygenase (decycling) 1
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
| Gene Name: | heme oxygenase (decycling) 1 |
| Synonyms: | HMOX1, BK286B10, HO-1, HSP32, Heat shock protein, 32-kD, Heme oxygenase (decycling) 1, Heme oxygenase 1, HO1 |
| Target Sequences: | NM_002133 NP_002124.1 P09601 |
Publications (3)
1
Resuscitation with PEGylated carboxyhemoglobin preserves renal cortical oxygenation and improves skeletal muscle microcirculatory flow during endotoxemia. Philippe Guerci, Bülent Ergin, Asli Kandil, Yasin Ince, Paul Heeman, Matthias Peter Hilty, Jan Bakker, Can Ince. American journal of physiology. Renal physiology. 2020 May;318:F1271-F1283. [Full Text Article]
[PubMed:32281418]
2
Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock. Philippe Guerci, Bulent Ergin, Aysegul Kapucu, Matthias P Hilty, Ronald Jubin, Jan Bakker, Can Ince. Anesthesiology. 2019 November;131:1110-1124. [Full Text Article]
[PubMed:31490291]
3
Elevated Heme Oxygenase-1 Correlates With Increased Brain Iron Deposition Measured by Quantitative Susceptibility Mapping and Decreased Hemoglobin in Patients With Parkinson's Disease. Jinghui Xu , Chi Xiao, Weizheng Song, Xiangqin Cui, Mengqiu Pan, Qun Wang, Yanqiu Feng, Yunqi Xu. Frontiers in aging neuroscience. 2021 Mar;13:656626. [Full Text Article]
[PubMed:33815094]
[PMC:PMC8012799]
☰ Filters
Products
Proteins
(20)
Type
Native
(1)
Over-Expression Lysate
(2)
Recombinant
(17)
Target
HMOX1 / HO-1
(20)
Publications
No
(20)
Tag
6His, N-terminus
(2)
6His-B2M, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(5)
His-GST
(1)
His-S
(3)
Myc-DDK (Flag)
(3)
Species
Bovine
(1)
Human
(9)
Mouse
(3)
Pig
(2)
Rat
(4)
Source
293T Cells
(1)
E. coli
(12)
HEK 293 Cells
(2)
Rat
(1)
Wheat Germ Extract
(2)
Yeast
(2)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(3)
Yeast
6His, N-terminus
34.93 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
E. coli
His
21.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
HEK 293 Cells
Myc-DDK (Flag)
32.6 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
32.6 kDa
20 µg/$150
E. coli
His
36.6 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
His
36.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST
57.42 kDa
10 µg/$479; 25 µg/$670
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
29.86kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
Myc-DDK (Flag)
32.6 kDa
100 µg/$494
Yeast
6His, N-terminus
35.0 kDa
100 µg/$499; 20 µg/$364; 1 mg/$1,683
E. coli
6His-B2M, N-terminus
46.9 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
29.9 kDa
10 µg/$376; 50 µg/$526
E. coli
His-S
18.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His-GST
65.0 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His-S
18.6 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
E. coli
His-S
16.4 kDa
10 µg/$263; 50 µg/$343; 100 µg/$530; 200 µg/$662; 1 mg/$1,657; 500 µg/$1,242; 5 mg/$2,600; 2 mg/$1,832
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