HMGN3

high mobility group nucleosomal binding domain 3

Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

HMGN3 (8)

Publications

No (8)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human HMGN3 Protein (Recombinant His) - LS-G3013

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human HMGN3 Protein (Recombinant GST) (Full Length) - LS-G31576

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

34.21 kDa

Price:

10 µg/$479; 25 µg/$670

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HMGN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107247

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

8.2 kDa

Price:

100 µg/$494

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HMGN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116785

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.5 kDa

Price:

100 µg/$494

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Human HMGN3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67125

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.5 kDa

Price:

20 µg/$1,107

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Human HMGN3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67127

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

8.2 kDa

Price:

20 µg/$1,107

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Human HMGN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79181

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

10.5 kDa

Price:

20 µg/$150

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Human HMGN3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79182

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

8.2 kDa

Price:

20 µg/$150

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