HLA-DRB3

Major Histocompatibility Complex, Class II, Dr Beta 3

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

☰ Filters

Products

Proteins (11)

Type

Over-Expression Lysate (10)

Recombinant (1)

Target

HLA-DRB3 (11)

Publications

No (11)

Tag

GST (1)

Myc-DDK (Flag) (10)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (9)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87995

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27 kDa

Price:

20 µg/$150

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111331

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.9 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111419

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115513

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110310

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130794

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.5 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118173

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.97 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118176

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.94 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118177

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.6 kDa

Price:

100 µg/$494

Select

HLA-DRB3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118175

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.67 kDa

Price:

100 µg/$494

Select

Human HLA-DRB3 Protein (Recombinant GST) (Full Length) - LS-G28841

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-11 of 11 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.