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HLA-DQB2

major histocompatibility complex, class II, DQ beta 2

HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.

Gene Name: major histocompatibility complex, class II, DQ beta 2
Synonyms: HLA-DQB2, MHC class II antigen DQB2, HLA-DXB
Target Sequences: M11136 P05538 P05538

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
HLA-DQB2 (5)
No (5)
GST (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
HLA-DQB2 Protein - 12.5% SDS-PAGE of human HLA-DQB2 stained with Coomassie Blue
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Wheat Germ Extract
GST
51.15 kDa
10 µg/$479; 25 µg/$670
HLA-DQB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.5 kDa
20 µg/$150
HLA-DQB2 Protein - Purified recombinant protein HLA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
27 kDa
20 µg/$1,107
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HEK 293 Cells
Myc-DDK (Flag)
26.5 kDa
20 µg/$1,107
HLA-DQB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27 kDa
100 µg/$494
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).