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HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants.

Gene Name: major histocompatibility complex, class II, DQ beta 1
Synonyms: HLA-DQB1, Lymphocyte antigen, MHC class II DQ beta chain, MHC class2 antigen, MHC class II antigen DQB1, HLA-DQB, IDDM1, CELIAC1, MHC DQ beta
Target Sequences: P01920

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Products
Antibodies (12)
Primary (12)
HLA-DQB1 (12)
Human (12)
Mouse (2)
Rat (2)
Bovine (1)
Monkey (1)
Sheep (1)
IHC (2)
IHC-P (1)
WB (7)
Flo (1)
ELISA (5)
IP (1)
rabbit (11)
mouse (1)
IgG (8)
polyclonal pc (12)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (9)
Internal (1)
aa13-39 (1)
No (12)
HLA-DQB1 Antibody - Immunohistochemistry of paraffin-embedded human lymph node tissue at dilution of 1:100
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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HLA-DQB1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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HLA-DQB1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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HLA-DQB1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
HLA-DQB1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using HLA-DQB1 Polyclonal Antibody at dilution of 1:30(×200)
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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HLA-DQB1 Mouse anti-Human Polyclonal Antibody
Human
Flo, WB
Unconjugated
50 µg/$705
HLA-DQB1 Antibody - HLA-DQB1 Antibody western blot of Daudi cell line lysates (35 ug/lane). The HLA-DQB1 antibody detected the HLA-DQB1 protein (arrow).
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HLA-DQB1 Rabbit anti-Human Polyclonal (aa13-39) Antibody
Human
WB
Unconjugated
400 µl/$393
HLA-DQB1 Antibody - Western blot of HLA-DQB1/B2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
HLA-DQB1 Antibody - Western blot analysis of HLA-DQB1 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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HLA-DQB1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Sheep, Bovine, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
HLA-DQB1 Antibody - Western blot testing of human SK-OV-3 cell lysate with HLA-DQB1 antibody at 0.5ug/ml. Predicted molecular weight ~30 kDa.
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
HLA-DQB1 Antibody - Western blot - Anti-HLA-DQB1/Hla Dqb1 Picoband antibody
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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HLA-DQB1 Rabbit anti-Human Polyclonal Antibody
Human
IP
Unconjugated
100 µl/$749
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).