HLA-DOB

major histocompatibility complex, class II, DO beta

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

HLA-DOB (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human HLA-DOB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65921

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.6 kDa

Price:

20 µg/$1,107

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Human HLA-DOB Protein (Recombinant GST, N-terminus) (aa27-116) - LS-G64547

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HLA-DOB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76535

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.6 kDa

Price:

20 µg/$150

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HLA-DOB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99657

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.6 kDa

Price:

100 µg/$494

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Human HLA-DOB Protein (Recombinant His) - LS-G2897

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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