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HLA-DMA

major histocompatibility complex, class II, DM alpha

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Gene Name: major histocompatibility complex, class II, DM alpha
Synonyms: HLA-DMA, DMA, RING6, D6S222E, HLADM, MHC class II antigen DMA
Target Sequences: NM_006120 NP_006111.2 P28067

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ELISA Kits (2)
Competitive EIA (1)
Sandwich (1)
HLA-DMA (2)
Human (1)
Rat (1)
96-Well Strip Plate (2)
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Cell Supernatant (1)
Plasma (2)
Serum (2)
HLA-DMA ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
HLA-DMA ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).