HLA-B

major histocompatibility complex, class I, B heavy chain

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

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Products

Antibodies (75)

Type

Primary (75)

Target

HLA-B (75)

Reactivity

Human (75)

Monkey (4)

Pig (8)

Application

IHC (8)

IHC-Fr (1)

IHC-P (10)

WB (40)

Flo (30)

Ctox (11)

ELISA (20)

ICC (1)

IF (7)

Peptide-ELISA (2)

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rabbit (38)

mouse (35)

goat (2)

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IHCPlus (4)

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Ig (1)

IgG (28)

IgG1 (9)

IgG2a (4)

IgG2b (2)

IgG3 (1)

IgG3,k (2)

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IgM,k (2)

Clonality

monoclonal mc (34)

polyclonal pc (41)

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2A11G7 (1)

2G7B10 (1)

4i115 (1)

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Epitope

aa26-309 (8)

aa62-90 (8)

aa182-208 (7)

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Publications

No (75)

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HLA-B Antibody (FITC) LS-C24497

Antibody:

HLA-B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

250 µl/$1,515

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HLA-B Antibody (FITC) LS-C24493

Antibody:

HLA-B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

250 µl/$1,201

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IHC-plus™ HLA-B Antibody LS-B15174

(4.0) Rating

Antibody:

HLA-B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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HLA-B Antibody (aa62-90) LS-C164912

Antibody:

HLA-B Rabbit anti-Human Polyclonal (aa62-90) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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HLA-B Antibody (aa26-309) LS-C314894

Antibody:

HLA-B Rabbit anti-Human Polyclonal (aa26-309) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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IHC-plus™ HLA-B Antibody LS-B11413

(4.0) Rating

Antibody:

HLA-B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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HLA-B Antibody (HRP) LS-C211404

Antibody:

HLA-B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-B Antibody (Biotin) LS-C211406

Antibody:

HLA-B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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HLA-B Antibody (FITC) LS-C211405

Antibody:

HLA-B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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HLA-B Antibody (FITC) LS-C24473

Antibody:

HLA-B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

250 µl/$1,201

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HLA-B Antibody (clone JOAN-1) LS-C123775

Antibody:

HLA-B Mouse anti-Human Monoclonal (JOAN-1) Antibody

Reactivity:

Human

Applications:

IHC-Fr

Format:

Unconjugated

Price:

100 µg/$688

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HLA-B Antibody (clone 4i115) LS-C24487

Antibody:

HLA-B Mouse anti-Human Monoclonal (4i115) Antibody

Reactivity:

Human

Applications:

Ctox

Format:

Unconjugated

Price:

100 µl/$1,321

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HLA-B Antibody LS-C24479

Antibody:

HLA-B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo

Format:

Unconjugated

Price:

100 µl/$1,295

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HLA-B Antibody (FITC) LS-C24484

Antibody:

HLA-B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

FITC Conjugated

Price:

500 µl/$1,400

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HLA-B Antibody LS-C24476

Antibody:

HLA-B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Unconjugated

Price:

100 µl/$1,223

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HLA-B Antibody (clone 2G7B10) LS-C682407

Antibody:

HLA-B Mouse anti-Human Monoclonal (2G7B10) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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HLA-B Antibody LS-C24466

Antibody:

HLA-B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Ctox, Flo

Format:

Unconjugated

Price:

100 µl/$1,223

Select

HLA-B Antibody LS-C24496

Antibody:

HLA-B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Ctox, Flo

Format:

Unconjugated

Price:

100 µl/$1,321

Select

HLA-B Antibody LS-C24490

Antibody:

HLA-B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Ctox, Flo

Format:

Unconjugated

Price:

100 µl/$1,321

Select

HLA-B Antibody (aa62-90) LS-C327581

Antibody:

HLA-B Rabbit anti-Human Polyclonal (aa62-90) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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HLA-B Antibody LS-C308249

Antibody:

HLA-B Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

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IHC-plus™ HLA-B Antibody LS-B15955

(4.0) Rating

Antibody:

HLA-B Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ HLA-B Antibody LS-B15956

(4.0) Rating

Antibody:

HLA-B Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

HLA-B Antibody LS-C673230

Antibody:

HLA-B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

HLA-B Antibody (N-Terminus) LS-C757861

Antibody:

HLA-B Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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