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HLA-B

major histocompatibility complex, class I, B heavy chain

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

Gene Name: major histocompatibility complex, class I, B heavy chain
Synonyms: HLA-B, HLAB, MHC Class I HLA heavy chain, Leukocyte antigen class I-B, SPDA1
Target Sequences: NM_005514 NP_005505.2 P01889

☰ Filters
Antibodies (75)
Proteins (7)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (75)
Recombinant (5)
Sandwich (1)
Sandwich CLIA (1)
HLA-B (84)
Human (77)
Monkey (4)
Pig (8)
IHC (8)
IHC-Fr (1)
IHC-P (10)
WB (40)
Flo (30)
Ctox (11)
ELISA (20)
ICC (1)
IF (7)
Peptide-ELISA (2)
rabbit (38)
mouse (35)
goat (2)
Product Group
IHCPlus (4)
Ig (1)
IgG (28)
IgG1 (9)
IgG2a (4)
IgG2b (2)
IgG3 (1)
IgG3,k (2)
IgM (14)
IgM,k (2)
monoclonal mc (34)
polyclonal pc (41)
2A11G7 (1)
2G7B10 (1)
4i115 (1)
EP-4 (2)
JOAN-1 (4)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (7)
BSA-free (2)
Concentrated (1)
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aa26-309 (8)
aa62-90 (8)
aa182-208 (7)
N-Terminus (1)
No (84)
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Serum (2)
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6His, N-terminus (1)
GST (1)
His (1)
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Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
Select
HLA-B Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
250 µl/$1,201
Select
HLA-B Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
250 µl/$1,515
HLA-B Protein
Select
E. coli
6His, N-terminus
36.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HLA-B Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HLA-B Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
HLA-B Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with HLA-B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
HLA-B Rabbit anti-Human Polyclonal (aa62-90) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
HLA-B Antibody - Anti-HLA-B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HLA-B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
HLA-B Antibody - Anti-HLA-B antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HLA-B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
HLA-B Antibody - Western blot of recombinant HLA-B.
Select
HLA-B Rabbit anti-Human Polyclonal (aa26-309) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Select
HLA-B Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
250 µl/$1,201
Select
HLA-B Mouse anti-Human Monoclonal (4i115) Antibody
Human
Ctox
Unconjugated
100 µl/$1,321
Select
HLA-B Mouse anti-Human Monoclonal (JOAN-1) Antibody
Human
IHC-Fr
Unconjugated
100 µg/$688
HLA-B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
Select
HLA-B Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µl/$1,295
Select
HLA-B Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo
FITC Conjugated
500 µl/$1,400
Select
HLA-B Mouse anti-Human Monoclonal Antibody
Human
Flo, IF
Unconjugated
100 µl/$1,223
HLA-B Antibody - Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using HLA-B mouse mAb with DAB staining.
Select
HLA-B Mouse anti-Human Monoclonal (2G7B10) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
Select
HLA-B Mouse anti-Human Monoclonal Antibody
Human
Ctox, Flo
Unconjugated
100 µl/$1,321
Select
HLA-B Mouse anti-Human Monoclonal Antibody
Human
Ctox, Flo
Unconjugated
100 µl/$1,321
Select
HLA-B Mouse anti-Human Monoclonal Antibody
Human
Ctox, Flo
Unconjugated
100 µl/$1,223
Select
HLA-B Rabbit anti-Human Polyclonal (aa62-90) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
HLA-B Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
HLA-B Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HLA-B Goat anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
HLA-B Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
HLA-B Goat anti-Human Polyclonal Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Select
E. coli
122 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
13.53 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
HLA-B Antibody - Immunohistochemistry image of paraffin-embedded human spleen tissue at a dilution of 1:100
Select
HLA-B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 84 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).