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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene Name: | histone cluster 2, H2bf |
Synonyms: | HIST2H2BF, Histone cluster 2, H2bf, Histone 2, H2bf, Histone H2B type 2-F |
Target Sequences: | Q5QNW6 Q5QNW6 |
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