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HIST1H2BA

histone cluster 1, H2ba

Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones. Also expressed maternally and is present in the female pronucleus, suggesting a similar role in protamine replacement by nucleosomes at fertilization (By similarity). Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene Name: histone cluster 1, H2ba
Synonyms: HIST1H2BA
Target Sequences: NP_733759.1

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Products
Antibodies (10)
Primary (10)
HIST1H2BA (10)
Human (10)
Mouse (1)
Rat (1)
IHC (3)
WB (10)
ELISA (7)
rabbit (8)
mouse (2)
IgG (7)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (8)
OTI1C9 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
Carrier-free (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (5)
aa1-30 (7)
aa2-127 (2)
No (10)
HIST1H2BA Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using HIST1H2BA Polyclonal Antibody at dilution of 1:45(×200)
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HIST1H2BA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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HIST1H2BA Mouse anti-Human Monoclonal (aa2-127) (Carrier-free) (OTI1C9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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HIST1H2BA Mouse anti-Human Monoclonal (aa2-127) (OTI1C9) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
Select
HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
HIST1H2BA Antibody - HIST1H2BA Antibody western blot of A549 cell line lysates (35 ug/lane). The HIST1H2BA Antibody detected the HIST1H2BA protein (arrow).
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HIST1H2BA Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).