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HIPK3 / FIST

homeodomain interacting protein kinase 3

Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).

Gene Name: homeodomain interacting protein kinase 3
Family/Subfamily: Protein Kinase , MNB/DYRK
Synonyms: HIPK3, ANPK, FIST, FIST3, Homolog of protein kinase YAK1, DYRK6, PKY, YAK1
Target Sequences: NM_005734 NP_005725.3 Q9H422

☰ Filters
Antibodies (21)
Proteins (5)
Over-Expression Lysate (2)
Primary (21)
Recombinant (3)
HIPK3 / FIST (26)
Human (21)
Mouse (2)
Rat (2)
Dog (1)
IHC (16)
IHC-P (3)
WB (10)
ELISA (15)
IF (1)
Peptide-ELISA (1)
rabbit (21)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (21)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (8)
aa1127-1156 (7)
Internal (6)
aa850-900 (1)
No (26)
GST, N-terminus (2)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
HIPK3 / FIST Antibody - Immunohistochemistry image of paraffin-embedded human bladder cancer at a dilution of 1:100
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
HIPK3 / FIST Antibody - Anti-HIPK3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa850-900) Antibody
Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
HIPK3 / FIST Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (aa1127-1156) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal (Internal) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
HIPK3 / FIST Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using HIPK3 Polyclonal Antibody at dilution of 1:60(×200)
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
HIPK3 / FIST Antibody - Western blot analysis of HIPK3 using HepG2 whole cells lysates
Select
HIPK3 / FIST Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HIPK3 / FIST Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HIPK3 / FIST Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HIPK3 / FIST Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
133.6 kDa
20 µg/$215
HIPK3 / FIST Protein - Recombinant Homeodomain Interacting Protein Kinase 3 (HIPK3) by SDS-PAGE
Select
E. coli
His, N-Terminal
33.1kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Viewing 1-25 of 26 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).