HGF / Hepatocyte Growth Factor

hepatocyte growth factor (hepapoietin A; scatter factor)

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

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Products

Proteins (33)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (7)

Recombinant (25)

Target

HGF / Hepatocyte Growth Factor (33)

Publications

No (33)

Tag

6His, C-terminus (2)

6His, N-terminus (3)

GST (2)

GST, N-terminus (2)

His (4)

His, N-terminus (1)

His,C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (7)

Species

Dog (1)

Human (22)

Mouse (4)

Rabbit (1)

Rat (2)

Source

293T Cells (3)

CHO Cells (1)

E. coli (10)

HEK 293 Cells (10)

High Five Cells (2)

Human Cells (1)

Insect Cells (1)

Mammalian Cells (3)

Wheat Germ Extract (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (11)

Biologically Active

Biologically active (8)

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G48

Source:

High Five Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Price:

2 µg/$268; 10 µg/$349

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Mouse HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G372

Source:

High Five Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Price:

5 µg/$268; 20 µg/$349

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Rat HGF / Hepatocyte Growth Factor Protein (Recombinant His, N-terminus) (aa306-471) - LS-G11375

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

20.4 kDa

Price:

10 µg/$307; 50 µg/$602; 100 µg/$962; 200 µg/$1,156; 1 mg/$2,369; 500 µg/$1,876; 5 mg/$4,201; 2 mg/$2,562

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant 6His, N-terminus) (Gln32-Ser728) - LS-G26962

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

80 kDa

Price:

10 µg/$289; 50 µg/$360

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HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121744

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.77 kDa

Price:

100 µg/$494

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HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121746

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.23 kDa

Price:

100 µg/$494

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G137618

Source:

Insect Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein.

Molecular Weight:

The alpha and beta chains contains 463 and 234 amino acids and have a predicted molecular mass of approximately 53.6 and 26 kD respectively. The predicted N-terminal amino acids are Gln and Val.

Price:

2 µg/$272; 10 µg/$352

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G133771

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

79.4 kDa or 68-85 kDa

Price:

5 µg/$268; 25 µg/$349

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G2941

Source:

E. coli

Tag:

None

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Dog HGF / Hepatocyte Growth Factor Protein (Recombinant His) (aa495-730) - LS-G23838

Source:

E. coli

Tag:

His

Molecular Weight:

30.0 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Rabbit HGF / Hepatocyte Growth Factor Protein (Recombinant His-T7) (aa32-494) - LS-G23839

Source:

E. coli

Tag:

His-T7

Molecular Weight:

57.2 kDa

Price:

10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164

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Rat HGF / Hepatocyte Growth Factor Protein (Recombinant GST) (aa477-728) - LS-G22408

Source:

E. coli

Tag:

GST

Molecular Weight:

55.4 kD

Price:

100 µg/$500; 20 µg/$364; 1 mg/$1,679

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Human HGF / Hepatocyte Growth Factor Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Gln32-Ser728) - LS-G26828

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

79.7 kDa

Price:

200 µl/$283

Select

Human HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate 6His, N-terminus) (Gln32-Ser728) - LS-G26680

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

79.7 kDa

Price:

100 µg/$298

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Human HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76423

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.77 kDa

Price:

20 µg/$150

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Human HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76422

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.13 kDa

Price:

20 µg/$215

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Human HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76426

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.23 kDa

Price:

20 µg/$150

Select

Human HGF / Hepatocyte Growth Factor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65863

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.6 kDa

Price:

20 µg/$1,107

Select

Human HGF / Hepatocyte Growth Factor Protein (Recombinant GST, N-terminus) (aa32-124) - LS-G58832

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

Select

Human HGF / Hepatocyte Growth Factor Protein (Recombinant GST, N-terminus) (aa619-728) - LS-G58833

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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HGF / Hepatocyte Growth Factor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99085

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.13 kDa

Price:

100 µg/$710

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G131466

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

10 µg/$395

Select

Human HGF / Hepatocyte Growth Factor Protein (Recombinant) - LS-G131469

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

1 mg/$7,939

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Mouse HGF / Hepatocyte Growth Factor Protein (Recombinant His) (aa496-728) - LS-G140841

Source:

E. coli

Sequence Length:

232 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

25.63 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Human HGF / Hepatocyte Growth Factor Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136770

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

79.7 kDa

Price:

50 µg/$516; 10 µg/$313; 1 mg/$2,837; 500 µg/$1,987

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