HFE2 / Hemojuvelin

hemochromatosis type 2 (juvenile)

HFE2 / Hemojuvelin is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

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Products

Proteins (12)

Type

Over-Expression Lysate (4)

Recombinant (8)

Target

HFE2 / Hemojuvelin (12)

Publications

No (12)

Tag

Fc (1)

GST, N-terminus (1)

His (2)

His-GST, N-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (10)

Source

293T Cells (2)

Baculovirus (1)

E. coli (4)

HEK 293 Cells (3)

Human (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human HFE2 / Hemojuvelin Protein (Recombinant His-T7) (aa29-401) - LS-G14602

Source:

E. coli

Tag:

His-T7

Molecular Weight:

43.5 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HFE2 / Hemojuvelin Protein (Recombinant GST, N-terminus) (aa93-173) - LS-G63721

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HFE2 / Hemojuvelin Protein (Recombinant) (aa36-400) - LS-G55929

Source:

Human

Tag:

None

Molecular Weight:

66.1kDa

Price:

50 µg/$882; 10 µg/$352; 200 µg/$1,529; 100 µg/$1,303; 1 mg/$2,845; 500 µg/$2,341; 5 mg/$6,161; 2 mg/$3,287

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Human HFE2 / Hemojuvelin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93957

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.5 kDa

Price:

20 µg/$150

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Human HFE2 / Hemojuvelin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93960

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.3 kDa

Price:

20 µg/$150

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Human HFE2 / Hemojuvelin Protein (Recombinant His) (aa234-416) - LS-G14598

Source:

E. coli

Tag:

His

Molecular Weight:

22 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HFE2 / Hemojuvelin Protein (Recombinant His-T7) (aa41-386) - LS-G14600

Source:

E. coli

Tag:

His-T7

Molecular Weight:

40.4 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HFE2 / Hemojuvelin Protein (Recombinant Fc) - LS-G24589

Source:

HEK 293 Cells

Tag:

Fc

Molecular Weight:

66.1 kDa

Price:

10 µg/$442; 50 µg/$882; 100 µg/$1,242

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HFE2 / Hemojuvelin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106716

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.5 kDa

Price:

100 µg/$494

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Human HFE2 / Hemojuvelin Protein (Recombinant His-GST, N-terminus) (Gln36-Phe200) - LS-G133239

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

47.4kDa

Price:

10 µg/$259; 50 µg/$331; 200 µg/$602; 100 µg/$482; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Human HFE2 / Hemojuvelin Protein (Recombinant His) (Met1-Ser399) - LS-G98597

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

40 kDa

Price:

100 µg/$721

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HFE2 / Hemojuvelin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103138

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.3 kDa

Price:

100 µg/$494

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