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HEXIM1

hexamethylene bis-acetamide inducible 1

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.

Gene Name:	hexamethylene bis-acetamide inducible 1
Synonyms:	HEXIM1, Cardiac lineage protein 1, CLP-1, EDG1, HMBA-inducible, Menage a quatre 1, Menage a quatre protein 1, Protein HEXIM1, MAQ1, HIS1
Target Sequences:	NM_006460 NP_006451.1 O94992

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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