HEXA

hexosaminidase A (alpha polypeptide)

HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

HEXA (10)

Publications

No (10)

Tag

GST (1)

His (3)

His, N-Terminal (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Source

293T Cells (1)

Baculovirus (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

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Human HEXA Protein (Recombinant His) - LS-G3329

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

50 µg/$361; 250 µg/$985; 10 µg/$261

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Mouse HEXA Protein (Recombinant His, N-Terminal) - LS-G132775

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28kDa

Price:

10 µg/$344; 50 µg/$837; 200 µg/$1,474; 100 µg/$1,253; 1 mg/$2,781; 500 µg/$2,276; 5 mg/$5,845; 2 mg/$3,119

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Human HEXA Protein (Recombinant GST) (Full Length) - LS-G28813

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.93 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HEXA Protein (Recombinant His) - LS-G2158

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human HEXA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74774

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.69 kDa

Price:

20 µg/$150

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Human HEXA Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65069

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58.3 kDa

Price:

20 µg/$1,107

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HEXA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99061

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.69 kDa

Price:

100 µg/$494

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Human HEXA Protein (Recombinant His-T7) (aa318-529) - LS-G11758

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.5 kDa

Price:

50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse HEXA Protein (Recombinant His-T7) (aa319-528) - LS-G11759

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.3 kDa

Price:

10 µg/$285; 50 µg/$465; 100 µg/$742; 200 µg/$930; 1 mg/$2,052; 500 µg/$1,586; 5 mg/$3,249; 2 mg/$2,241

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Human HEXA Protein (Recombinant His) (Met1-Thr529) - LS-G97533

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.7 kDa

Price:

50 µg/$970

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