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HES6
hes family bHLH transcription factor 6
This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.
| Gene Name: | hes family bHLH transcription factor 6 |
| Synonyms: | HES6, C-HAIRY1, BHLHc23, HES-6, BHLHb41, Hairy and enhancer of split 6, Transcription cofactor HES-6 |
| Target Sequences: | NM_018645 NP_061115.2 Q96HZ4 |
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