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HERPUD1 / HERP

Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined.

Gene Name: Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Synonyms: HERPUD1, HERP, Mif1, KIAA0025, SUP, MMS-inducible
Target Sequences: NM_014685 NP_055500.1 Q15011

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Products
Proteins (13)
Over-Expression Lysate (6)
Recombinant (7)
HERPUD1 / HERP (13)
No (13)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (9)
Human (10)
293T Cells (3)
E. coli (1)
HEK 293 Cells (6)
Wheat Germ Extract (3)
Purified (3)
HERPUD1 / HERP Protein - Purified recombinant protein HERPUD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
43.5 kDa
20 µg/$1,107
HERPUD1 / HERP Protein - Purified recombinant protein HERPUD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
43.4 kDa
20 µg/$1,107
HERPUD1 / HERP Protein - Purified recombinant protein HERPUD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
40.7 kDa
20 µg/$1,107
HERPUD1 / HERP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
43.4 kDa
20 µg/$150
HERPUD1 / HERP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.7 kDa
20 µg/$150
HERPUD1 / HERP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
43.5 kDa
20 µg/$150
HERPUD1 / HERP Protein - 12.5% SDS-PAGE of human HERPUD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.75 kDa
2 µg/$439
HERPUD1 / HERP Protein - 12.5% SDS-PAGE of human HERPUD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
68.75 kDa
10 µg/$479; 25 µg/$670
HERPUD1 / HERP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
43.5 kDa
100 µg/$494
HERPUD1 / HERP Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
HERPUD1 / HERP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
43.4 kDa
100 µg/$494
HERPUD1 / HERP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
40.7 kDa
100 µg/$494
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).