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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HECW1

HECT, C2 And WW Domain Containing E3 Ubiquitin Protein Ligase 1

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Gene Name: HECT, C2 And WW Domain Containing E3 Ubiquitin Protein Ligase 1
Synonyms: HECW1, HNEDL1, HECT type E3 ubiquitin ligase, NEDL1, KIAA0322
Target Sequences: AB002320 BAA20780.2 Q76N89

Filtered By: None
Type
Over-Expression Lysate (2)
Target
HECW1 (2)
Tag
Myc + DDK (2)
Species
Human (1)
Source
293T Cells (1)
HEK 293 Cells (1)
Showing 1-2 of 2 results

Human HECW1 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G79736
293T Cells
1661 AA
Myc + DDK
179.4 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

HECW1 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G113488
HEK 293 Cells
1661 AA
Myc + DDK
179.4 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Showing 1-2 of 2 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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