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HDAC8

histone deacetylase 8

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Gene Name: histone deacetylase 8
Family/Subfamily: Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms: HDAC8, CDLS5, HD8, HDACL1, Histone deacetylase 8, MRXS6, RPD3, CDA07, Histone deacetylase-like 1, WTS
Target Sequences: NM_018486 NP_060956.1 Q9BY41

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
HDAC8 (11)
No (11)
GST (2)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (4)
Human (8)
Mouse (1)
293T Cells (2)
Baculovirus (2)
E. coli (2)
HEK 293 Cells (2)
Sf9 Cells (1)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (2)
HDAC8 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HDAC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.4 kDa
20 µg/$150
HDAC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41.6 kDa
20 µg/$150
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Baculovirus
GST
Less than 1.0 EU/µg protein (determined by LAL method).
68 kDa
100 µg/$721
HDAC8 Protein
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E. coli
His-SUMO
57.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HDAC8 Protein - 12.5% SDS-PAGE of human HDAC8 stained with Coomassie Blue
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Wheat Germ Extract
GST
66.99 kDa
10 µg/$479; 25 µg/$670
HDAC8 Protein
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E. coli
His, N-Terminal
41.6 kDa
50 µg/$419
HDAC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.4 kDa
100 µg/$494
HDAC8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.6 kDa
100 µg/$494
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
43.1 kDa
100 µg/$843
HDAC8 Protein
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Sf9 Cells
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Viewing 1-11 of 11 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).