HDAC3

histone deacetylase 3

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.

☰ Filters

Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

HDAC3 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His-GST (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

Baculovirus (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Select

Human HDAC3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65917

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.7 kDa

Price:

20 µg/$1,107

Select

Human HDAC3 Protein (Recombinant GST, N-terminus) (aa319-428) - LS-G60895

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human HDAC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76522

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.7 kDa

Price:

20 µg/$150

Select

Human HDAC3 Protein (Recombinant His-GST) (Met1-Ile428) - LS-G97531

Source:

Baculovirus

Tag:

His-GST

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

76.7 kDa

Price:

50 µg/$721

Select

Human HDAC3 Protein (Recombinant His-SUMO) (Full Length) - LS-G20813

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

64.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human HDAC3 Protein (Recombinant GST) (Full Length) - LS-G31360

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.82 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human HDAC3 Protein (Recombinant 6His, N-terminus) (Ala2-Ile428) - LS-G26592

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

51 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949

Select

HDAC3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100163

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.7 kDa

Price:

100 µg/$494

Viewing 1-8 of 8 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.