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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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HDAC11

histone deacetylase 11

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Gene Name: histone deacetylase 11
Family/Subfamily: Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms: HDAC11, HD11, Histone deacetylase 11
Target Sequences: NM_024827 NP_079103.2 Q96DB2

Publications (1)

1
A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. Keedy KS, Archin NM, Gates AT, Espeseth A, Hazuda DJ, Margolis DM. Journal of virology. 2009 83:4749-56. [PubMed:19279091] [PMC:PMC2682072] Related Antibodies: LS-C98651.

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Viewing 1-7 of 7 items
HDAC11 Protein - Purified recombinant protein HDAC11 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc + DDK
39 kDa
20µg   $890.00
HDAC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc + DDK
32.9 kDa
20µg   $195.00
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293T Cells
Myc + DDK
39 kDa
20µg   $195.00
HDAC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc + DDK
32.9 kDa
100µg   $365.00
HDAC11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc + DDK
39 kDa
100µg   $365.00
HDAC11 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST,N-terminus
1mg   $1,290.00; 500µg   $830.00; 200µg   $485.00; 100µg   $355.00; 50µg   $275.00; 10µg   $245.00
HDAC11 Protein - 12.5% SDS-PAGE of human HDAC11 stained with Coomassie Blue
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Wheat Germ Extract
GST
63.91 kDa
10µg   $425.00; 25µg   $590.00

Viewing 1-7 of 7 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).