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HDAC11

histone deacetylase 11

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Gene Name:	histone deacetylase 11
Family/Subfamily:	Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms:	HDAC11, HD11, Histone deacetylase 11
Target Sequences:	NM_024827 NP_079103.2 Q96DB2

Publications (1)

A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. Keedy KS, Archin NM, Gates AT, Espeseth A, Hazuda DJ, Margolis DM. Journal of virology. 2009 83:4749-56. [PubMed:19279091] [PMC:PMC2682072] Related Antibodies: LS-C98651.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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