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HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.
| Gene Name: | hyperpolarization activated cyclic nucleotide-gated potassium channel 2 |
| Family/Subfamily: | Ion Channel , Potassium channel - cyclic nucleotide gated |
| Synonyms: | HCN2, BCNG2, BCNG-2, HAC-1, HAC1 |
| Target Sequences: | NM_001194 NP_001185.3 Q9UL51 |
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