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HCAR3 / GPR109B / HM74

hydroxycarboxylic acid receptor 3

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Gene Name:	hydroxycarboxylic acid receptor 3
Family/Subfamily:	GPCR , Nicotinic Acid
Synonyms:	HCAR3, GPR109B, GTP-binding protein, NIACR2, HM74, HM74b, Nicotinic acid receptor 2, Putative chemokine receptor, Niacin receptor 2, Puma-g, HCA3, PUMAG
Target Sequences:	NM_006018 NP_006009.2 P49019

HCAR3 / GPR109B / HM74 Protein - 12.5% SDS-PAGE of human GPR109B stained with Coomassie Blue

Human HCAR3 / GPR109B / HM74 Protein (Recombinant GST) (Full Length) - LS-G31361

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.9 kDa

Price:

2 µg/$439

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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