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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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HBXIP

late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.

Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Synonyms: LAMTOR5, HBXIP, XIP
Target Sequences: NM_006402 NP_006393.2 O43504

☰ Filters
HBXIP (18)
IgG (12)
No (18)
Viewing 1-18 of 18 items
HBXIP Antibody - Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Mouse, Human
IHC-P, WB
Unconjugated
50µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
Unconjugated
100µg   $605.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
HRP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
Biotin Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
FITC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
AP Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
APC Conjugated
100µl   $755.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
WB
PE Conjugated
100µl   $755.00
HBXIP Antibody - HBXIP antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human HBXIP
Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
HBXIP Antibody - HBXIP antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human HBXIP
Human
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
HBXIP Antibody - HBXIP antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human HBXIP
Human
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
HBXIP Antibody - HBXIP antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human HBXIP
Human
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
ELISA, IHC, WB
Unconjugated
100µg   $355.00
HBXIP Antibody
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
HBXIP Antibody - Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $235.00; 100µl   $285.00
Select
Rabbit Polyclonal to Human HBXIP
Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human HBXIP
Mouse, Human
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
HBXIP Antibody
Select
Rabbit Polyclonal to Human HBXIP
Human
WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00

Viewing 1-18 of 18 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).