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Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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HBG1 / Fetal Hemoglobin
hemoglobin, gamma A
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
| Gene Name: | hemoglobin, gamma A |
| Synonyms: | HBG1, A-gamma globin, Hemoglobin gamma-A chain, Hb F Agamma, HBGA, Hemoglobin subunit gamma-1, Hemoglobin, gamma A, Fetal Hemoglobin, Gamma A hemoglobin, Gamma-1-globin, HSGGL1, PRO2979, Gamma globin, HBGR, Hemoglobin gamma-1 chain, Hemoglobin gamma-a |
| Target Sequences: | NM_000559 NP_000550.2 P69891 |
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