HBEGF / HB EGF

heparin-binding EGF-like growth factor

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

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Products

Proteins (15)

Type

Over-Expression Lysate (2)

Recombinant (13)

Target

HBEGF / HB EGF (15)

Publications

No (14)

Yes (1)

Tag

6His, C-terminus (2)

GST (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (11)

Mouse (2)

Source

293T Cells (1)

CHO Cells (1)

E. coli (9)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (9)

Biologically Active

Biologically active (8)

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Human HBEGF / HB EGF Protein (Recombinant) - LS-G27105

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

12-14 kDa (SDS-PAGE)

Price:

5 µg/$239; 25 µg/$286; 1 mg/$1,148

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HBEGF / HB EGF Protein (Recombinant) (Asp63-Leu148) - LS-G27078

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

14 kDa (SDS-PAGE)

Price:

50 µg/$300; 10 µg/$253; 1 mg/$1,148

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Human HBEGF / HB EGF Protein (Recombinant) - LS-G145773

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

9.7 kDa

Price:

10 µg/$278; 1 mg/$1,470; 50 µg/$364

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Mouse HBEGF / HB EGF Protein (Recombinant) - LS-G145774

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

9.8 kDa

Price:

10 µg/$278; 1 mg/$1,475; 50 µg/$364

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Human HBEGF / HB EGF Protein (Recombinant GST) (Full Length) - LS-G28261

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

46.53 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HBEGF / HB EGF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76416

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.9 kDa

Price:

20 µg/$150

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HBEGF / HB EGF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99601

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.9 kDa

Price:

100 µg/$494

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Human HBEGF / HB EGF Protein (Recombinant) (aa63-148) - LS-G5807

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

9.7 kDa

Price:

10 µg/$282; 100 µg/$503; 500 µg/$1,058

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Human HBEGF / HB EGF Protein (Recombinant) - LS-G49

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

9.7 kDa

Price:

10 µg/$268; 50 µg/$349

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Human HBEGF / HB EGF Protein (Recombinant) - LS-G131412

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~10.1 kDa

Price:

50 µg/$291; 200 µg/$437; 1 mg/$1,123

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Human HBEGF / HB EGF Protein (Recombinant 6His, C-terminus) (Leu20-Leu148) - LS-G40338

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1kD

Price:

10 µg/$248; 50 µg/$295; 500 µg/$693; 1 mg/$995

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Human HBEGF / HB EGF Protein (Recombinant) - LS-G137820

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 86 amino acid recombinant protein has a predicted molecular mass of approximately 9.7 kD. The DTT-reduced and non-reduced protein migrate at approximately 13 kD and 16 kD respectively by SDS-PAGE. The predicted N-terminal amino acid is Asp.

Price:

10 µg/$268; 25 µg/$306

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Human HBEGF / HB EGF Protein (Recombinant 6His, C-terminus) (Leu20-Leu148) - LS-G138653

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1 kDa

Price:

10 µg/$248; 50 µg/$296

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Human HBEGF / HB EGF Protein (Recombinant His) (aa21-160) - LS-G13875

Source:

E. coli

Tag:

His

Molecular Weight:

17.2 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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Mouse HBEGF / HB EGF Protein (Recombinant His-T7) (aa25-160) - LS-G13876

Source:

E. coli

Tag:

His-T7

Molecular Weight:

18.9 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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