HAVCR2 / TIM-3

hepatitis A virus cellular receptor 2

HAVCR2 / TIM-3 belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

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Products

Proteins (46)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (42)

Target

HAVCR2 / TIM-3 (46)

Application

SDS-PAGE (4)

Publications

No (46)

Tag

6His, C-terminus (5)

6His, N-terminus (1)

8His, N-terminus (1)

AVI-Fc, C-terminus (1)

DDK (Flag)-His, C-terminus (1)

Fc (1)

Fc, C-terminus (6)

Fc/6His,C-terminus (1)

Fc-6His, C-terminus (2)

Fc-AVI, C-terminus (1)

GST (1)

His (3)

His, N-Terminal (5)

His,C-terminus (5)

His,N-terminus (1)

His-T7 (1)

Human IgG Fc, C-terminus (2)

Human IgG1 Fc (2)

mFc, C-terminus (1)

Mouse IgG2 Fc (1)

Mouse IgG2a Fc, N-terminus (1)

Myc-DDK (Flag) (2)

more less

Species

Crab-eating macaque (2)

Cynomolgus (2)

Human (26)

Marmoset (2)

Mouse (13)

Source

293T Cells (1)

CHO Cells (3)

E. coli (4)

HEK 293 Cells (12)

Human Cells (10)

Mammalian Cells (14)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (16)

Supernatant (1)

Low Endotoxin Level

Low endotoxin level (33)

Biologically Active

Biologically active (4)

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Human HAVCR2 / TIM-3 Protein (Recombinant His, N-Terminal) - LS-G2093

Source:

E. coli

Tag:

His, N-Terminal

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human HAVCR2 / TIM-3 Protein (Recombinant 6His, C-terminus) (Ser22-Arg200) - LS-G38879

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

20.86kD

Price:

10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157

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Human HAVCR2 / TIM-3 Protein (Recombinant Mouse IgG2 Fc) (aa22-200) - LS-G4072

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$519

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Human HAVCR2 / TIM-3 Protein (Recombinant His,C-terminus) (Met1-Arg200) - LS-G48055

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human HAVCR2 consists of 190 amino acids and predicts a molecular mass of 21.3 kDa.

Price:

100 µg/$480; 1 mg/$2,324

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Human HAVCR2 / TIM-3 Protein (Recombinant His) (Met1-Arg200) - LS-G97947

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.4 kDa

Price:

100 µg/$843; 1 mg/$5,007

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Human HAVCR2 / TIM-3 Protein (Recombinant Human IgG1 Fc) (aa22-200) - LS-G4061

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$519

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Human HAVCR2 / TIM-3 Protein (Recombinant Fc-6His, C-terminus) - LS-G136772

Source:

Mammalian Cells

Tag:

Fc-6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.7 kDa

Price:

50 µg/$414; 10 µg/$279; 1 mg/$2,837; 500 µg/$1,987

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Human HAVCR2 / TIM-3 Protein (Recombinant AVI-Fc, C-terminus) - LS-G136774

Source:

Mammalian Cells

Tag:

AVI-Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.8 kDa

Price:

100 µg/$1,177; 20 µg/$489

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) - LS-G136777

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.3 kDa

Price:

50 µg/$385; 10 µg/$284; 1 mg/$2,321; 500 µg/$1,666

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Mouse IgG2a Fc, N-terminus) - LS-G134284

Source:

HEK 293 Cells

Tag:

Mouse IgG2a Fc, N-terminus

Endotoxin Level:

Less than 5.0 EU/mg protein (determined by LAL method).

Molecular Weight:

~65 kDa (SDS-PAGE)

Price:

100 µg/$519

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Cynomolgus HAVCR2 / TIM-3 Protein (Recombinant 8His, N-terminus) - LS-G137908

Source:

Mammalian Cells

Tag:

8His, N-terminus

Endotoxin Level:

Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,262; 1 mg/$1,627

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Human HAVCR2 / TIM-3 Protein (Recombinant Fc-AVI, C-terminus) (Ser22-Arg200) - LS-G138363

Source:

Mammalian Cells

Tag:

Fc-AVI, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.8 kDa

Price:

20 µg/$416; 100 µg/$910

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Human HAVCR2 / TIM-3 Protein (Recombinant Fc/6His,C-terminus) (Ser22-Arg200) - LS-G138899

Source:

Mammalian Cells

Tag:

Fc/6His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.7 kDa

Price:

10 µg/$262; 50 µg/$361

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) (Arg20-Arg191) - LS-G138871

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.3 kDa

Price:

10 µg/$266; 50 µg/$339

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Human HAVCR2 / TIM-3 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Arg200) - LS-G141217

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human HAVCR2 consists of 417 amino acids and predicts a molecular mass of 46.6 kDa.

Price:

100 µg/$441; 1 mg/$2,003

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Mouse HAVCR2 / TIM-3 Protein (Recombinant His,C-terminus) (Met1-Arg191) - LS-G141223

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse HAVCR2 comprises 181 amino acids and has a predicted molecular mass of 20.3 kDa. The apparent molecular mass of the protein is approximately 37-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human HAVCR2 / TIM-3 Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142261

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

23 kDa

Price:

20 µg/$1,107

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Human HAVCR2 / TIM-3 Protein (Recombinant Fc, C-terminus) - LS-G142262

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Molecular Weight:

45 kDa

Price:

20 µg/$1,107

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Human HAVCR2 / TIM-3 Protein (Recombinant mFc, C-terminus) (Ser22-Arg200) - LS-G139839

Source:

Mammalian Cells

Tag:

mFc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.4 kDa

Price:

10 µg/$288; 50 µg/$436

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Human HAVCR2 / TIM-3 Protein (Recombinant His) (aa22-202) - LS-G20808

Source:

E. coli

Tag:

His

Molecular Weight:

24.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HAVCR2 / TIM-3 Protein (Recombinant His-T7) (aa22-202) - LS-G25940

Source:

E. coli

Tag:

His-T7

Molecular Weight:

23.7 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human HAVCR2 / TIM-3 Protein (Recombinant GST) (Full Length) - LS-G35843

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.36 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HAVCR2 / TIM-3 Protein (Recombinant 6His, N-terminus) (aa22-202) - LS-G57184

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Mouse HAVCR2 / TIM-3 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Arg191) - LS-G49185

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse HAVCR2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 411 amino acids and has a predicted molecular mass of 45.9 kDa. The apparent molecular mass of the protein is approximately 58-66 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human HAVCR2 / TIM-3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85542

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.2 kDa

Price:

20 µg/$150

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