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HARS2

histidyl-tRNA synthetase 2, mitochondrial

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.

Gene Name: histidyl-tRNA synthetase 2, mitochondrial
Synonyms: HARS2, HARSR, Histidine--tRNA ligase-like, Histidine translase, HARSL, Histidine-tRNA ligase homolog, Histidyl-tRNA synthetase, HO3, PRLTS2, HARS-related, HisRS, Histidyl-tRNA synthetase-like
Target Sequences: U18937 AAA73974.1 P49590

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
HARS2 (5)
No (5)
GST, N-terminus (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
HARS2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HARS2 Protein - Purified recombinant protein HARS2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.3 kDa
20 µg/$1,107
HARS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56.89 kDa
20 µg/$150
HARS2 Protein
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E. coli
His-SUMO
69.3 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HARS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.89 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).