HACE1

HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

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Products

ELISA Kits (6)

Type

Custom (4)

Sandwich (2)

Target

HACE1 (6)

Reactivity

Human (2)

Mouse (1)

Rat (1)

Chicken (1)

Format

96-Well Strip Plate (6)

Publications

No (6)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

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Mouse HACE1 (Custom ELISA) ELISA Kit - LS-F19952

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken HACE1 (Custom ELISA) ELISA Kit - LS-F19950

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Rat HACE1 (Custom ELISA) ELISA Kit - LS-F19951

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine HACE1 (Custom ELISA) ELISA Kit - LS-F19953

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human HACE1 (Sandwich ELISA) ELISA Kit - LS-F33910

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human HACE1 (Sandwich ELISA) ELISA Kit - LS-F11601

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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